22.2% Fenbendazole Granule
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Pharmacological action
helminthagogue. Fenbendazole has broad-spectrum anthelmintic effect on nematode, tapeworm and fluke and no effect on blood flukes. The mechanism of action of Fenbendazole is mainly by binding with microtubulin in sensitive polypide, to prevent its multimerization with α-microtubulin to form microtubule, thus to influence mitosis, protein device and energy metabolism etc reproduction procedure of polypide cells. After oral administration, only a few will be absorbed. It is absorbed slowly in ruminant and a litter quick in monogastric animal. After oral administration to dog, plasma concentration peak time is 24 h; to sheep, it is 2~3 days. Fenbendazole will metabolize to sulfoxide (oxfendazole with activity) and sulphone after entering in body. In cattle, sheep and pig, 44%~50% of Fenbendazole will be excreted along with excrement in the original shape, and only less than 1% is excreted along with urine.
Main components
22.2% Fenbendazole
Appearance
22.2% Fenbendazole granule is almost white granule
Indications
Treatment of nematodosis and teniasis in livestock and poultry.
Dosage and administration
Calculated with Fenbendazole. Oral solution: single dose:
Horse, cattle, sheep and pig: 5~7.5mg/kg body weight;
Dog, cat: 5~50mg/body weight;
Poultry: 10~50mg/body weight.
Withdrawal period
Cattle, sheep: 14 days;
Pig: 3 days;
Milk: 7 days;
Poultry: 28 days.
Side effects
Dogs and cats show emesis occasionally by oral administration.
Storage
Store in the place below 30℃.
Please put 22.2% Fenbendazole granule out of the reach of children.
Hebei Veyong pharmaceutical Co., Ltd, was established in 2002, located in Shijiazhuang City, Hebei Province, China, next to the Capital Beijing. She is a large GMP-certified veterinary drug enterprise, with R&D, production and sales of veterinary APIs, preparations, premixed feeds and feed additives. As Provincial Technical Center, Veyong has established an innovated R&D system for new veterinary drug, and is the nationally known technological innovation based veterinary enterprise, there are 65 technical professionals. Veyong has two production bases: Shijiazhuang and Ordos, of which the Shijiazhuang base covers an area of 78,706 m2, with 13 API products including Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, and 11 preparation production lines including injection, oral solution, powder, premix, bolus, pesticides and disinfectant, ects. Veyong provides APIs, more than 100 own- label preparations, and OEM & ODM service.
Veyong attaches great importance to the management of EHS(Environment, Health& Safety) system, and obtained the ISO14001 and OHSAS18001 certificates. Veyong has been listed in the strategic emerging industrial enterprises in Hebei Province and can ensure the continuous supply of products.
Veyong established the complete quality management system, obtained the ISO9001 certificate, China GMP certificate, Australia APVMA GMP certificate, Ethiopia GMP certificate, Ivermectin CEP certificate, and passed US FDA inspection. Veyong has professional team of registeration, sales and technical service, our company has gained reliance and support from numerous customers by excellent product quality, high-quality pre-sales and after-sales service, serious and scientific management. Veyong has made long term cooperation with many internationally known animal pharmaceutical enterprises with products exported to the Europe, South America, Middle East, Africa, Asia, etc. more than 60 countries and regions.
