Amoxicillin & Colistin Sulfate Soluble Powder
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Composition Per Gram
Amoxiciline Trihydrate............... 260MG
Collistine............................................1,000.000IU
Description
The combination of amoxycillin and colistin acts additive. Amoxycillin is a semisynthetic broadspectrum penicillin with a bactericidal action against both Gram-positive and Gram-negative bacteria. The spectrum of amoxycillin includes Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase-negative Staphylococcus and Streptococcus, spp. The bactericidal action is due to inhibition of cell wall synthesis.
Amoxicillin is mainly excreted in urine. A major part can also be excreted in bile. Colistin is an antibiotic from the group of polymyxins with a bactericidal action against Gram-negative bacteria like E. coli, Haemophilus and Salmonella. Since colistin is absorbed for a very small part after oral administration only gastrointestinal indications are relevant.
Indications
Gastrointestinal, respiratory and urinary tract infections caused by amoxicillin and colistin sensitive micro-organisms, like Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase negative Staphylococcus and Streptococcus spp. in calves, goats, poultry, sheep and swine.
Contra indications
Hypersensitivity to amoxicillin and/or colistin.
Administration to animals with a seriously impaired renal function.
Concurrent administration of tetracyclines, chloramphenicol, macrolides and lincosamides.
Administration to animals with an active microbial digestion.
Dosage
For oral administration:
Calves, goats and sheep:
Twice daily 5 g per 100 kg body weight for 3 - 5 days.
Poultry and swine:
1 kg per 1000 - 2000 litres of drinking water for 3 - 5 days.
Note: for pre-ruminant calves, lambs and kids only.
Before adding to the drinking water make a presolution of 1 kg Amoxicol per 20 litres of water with a temperature of 40 °C.
Side effects
Hypersensitivity reactions, renal dysfunction, neurotoxicity and neuromuscular blockade.
Withdrawal times
For meat: 8 days.
Storage
Store in the place below 30℃,keep dry and cool.
Hebei Veyong pharmaceutical Co., Ltd, was established in 2002, located in Shijiazhuang City, Hebei Province, China, next to the Capital Beijing. She is a large GMP-certified veterinary drug enterprise, with R&D, production and sales of veterinary APIs, preparations, premixed feeds and feed additives. As Provincial Technical Center, Veyong has established an innovated R&D system for new veterinary drug, and is the nationally known technological innovation based veterinary enterprise, there are 65 technical professionals. Veyong has two production bases: Shijiazhuang and Ordos, of which the Shijiazhuang base covers an area of 78,706 m2, with 13 API products including Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, and 11 preparation production lines including injection, oral solution, powder, premix, bolus, pesticides and disinfectant, ects. Veyong provides APIs, more than 100 own- label preparations, and OEM & ODM service.
Veyong attaches great importance to the management of EHS(Environment, Health& Safety) system, and obtained the ISO14001 and OHSAS18001 certificates. Veyong has been listed in the strategic emerging industrial enterprises in Hebei Province and can ensure the continuous supply of products.
Veyong established the complete quality management system, obtained the ISO9001 certificate, China GMP certificate, Australia APVMA GMP certificate, Ethiopia GMP certificate, Ivermectin CEP certificate, and passed US FDA inspection. Veyong has professional team of registeration, sales and technical service, our company has gained reliance and support from numerous customers by excellent product quality, high-quality pre-sales and after-sales service, serious and scientific management. Veyong has made long term cooperation with many internationally known animal pharmaceutical enterprises with products exported to the Europe, South America, Middle East, Africa, Asia, etc. more than 60 countries and regions.
