15% Amoxicillin Injection
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Indication
Amoxicillin Injection is a suspension of fine particles. After standing, the fine particles sink and become a uniform off-white suspension after shaking. [Pharmacological action] Amoxicillin inhibits the synthesis of bacterial cell walls, so that the bacteria in the growth phase quickly become spheroids and rupture and lyse bacteria. It is good for various Streptococcus, penicillinase-non-producing Staphylococcus, Clostridium and other Gram-positive bacteria, and Pasteurella, Mannheimia hemolyticus, Escherichia coli, Salmonella and other Gram-negative bacteria. The antibacterial activity.
After intramuscular injection in pigs and cattle, the bioavailability is 60% to 100%, and the peak plasma concentration of 1.5 to 4.5 µg/ml is reached 1 to 3 hours after injection. After pigs and cows were injected with this product, the blood drug concentration above MIC90 was maintained for 36 hours and 72 hours, respectively. After repeated injections (48 hours between two injections), the pharmacokinetic parameters are stable and there is no accumulation effect. It is mainly excreted through the kidneys in active form.
Drug interactions Macrolides, sulfonamides and tetracycline antibiotics inhibit bacterial protein synthesis. Simultaneous use of these antibiotics can reduce the bactericidal effect of amoxicillin.
Indications: It is used for the infection of gram-positive bacteria and gram-negative bacteria caused by amoxicillin-sensitive bacteria in pigs and cattle.
Dosage and administration
Calculated as amoxicillin. Intramuscular injection: a single dose, 15 mg for pig and cattle for each 1 kg of body weight. Another injection may be given after 48 hours if needed.
Precautions
(1) 15% Amoxicillin injection is contraindicated in animals allergic to penicillins.
(2) It is contraindicated in affected animals with severe renal insufficiency.
(3) Shake well before use.
(4) No more than 20 ml per injection site.
Adverse reactions
Administration of this product may lead to allergic phenomena, and occasionally severe allergic reactions (such as anaphylactic shock).
Withdrawal period
16 days for cattle, 20 days for pigs and 3 days for abstinence period.
Storage
Sealed and stored in a cool place.
Hebei Veyong pharmaceutical Co., Ltd, was established in 2002, located in Shijiazhuang City, Hebei Province, China, next to the Capital Beijing. She is a large GMP-certified veterinary drug enterprise, with R&D, production and sales of veterinary APIs, preparations, premixed feeds and feed additives. As Provincial Technical Center, Veyong has established an innovated R&D system for new veterinary drug, and is the nationally known technological innovation based veterinary enterprise, there are 65 technical professionals. Veyong has two production bases: Shijiazhuang and Ordos, of which the Shijiazhuang base covers an area of 78,706 m2, with 13 API products including Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, and 11 preparation production lines including injection, oral solution, powder, premix, bolus, pesticides and disinfectant, ects. Veyong provides APIs, more than 100 own- label preparations, and OEM & ODM service.
Veyong attaches great importance to the management of EHS(Environment, Health& Safety) system, and obtained the ISO14001 and OHSAS18001 certificates. Veyong has been listed in the strategic emerging industrial enterprises in Hebei Province and can ensure the continuous supply of products.
Veyong established the complete quality management system, obtained the ISO9001 certificate, China GMP certificate, Australia APVMA GMP certificate, Ethiopia GMP certificate, Ivermectin CEP certificate, and passed US FDA inspection. Veyong has professional team of registeration, sales and technical service, our company has gained reliance and support from numerous customers by excellent product quality, high-quality pre-sales and after-sales service, serious and scientific management. Veyong has made long term cooperation with many internationally known animal pharmaceutical enterprises with products exported to the Europe, South America, Middle East, Africa, Asia, etc. more than 60 countries and regions.
