Amoxicillin Soluble Powder
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Pharmacological action
Pharmacodynamics
Amoxicillin is a β-lactam antibiotic with broad-spectrum antibacterial effect. The antibacterial spectrum and antibacterial activity are basically the same as those of ampicillin, and the antibacterial activity against most Gram-positive bacteria is slightly weaker than that of penicillin. It has a strong effect on Gram-negative bacteria such as Escherichia coli, Proteus, Salmonella, Haemophilus, Brucella and Pasteurella, but these bacteria are prone to drug resistance. Not susceptible to Pseudomonas aeruginosa. Because its absorption in monogastric animals is better than that of ampicillin and its blood concentration is higher, it has better curative effect on systemic infection. It is suitable for systemic infections such as respiratory system, urinary system, skin and soft tissue caused by sensitive bacteria.
Pharmacokinetics
Amoxicillin is quite stable to gastric acid, and 74% to 92% is absorbed after oral administration in monogastric animals. The contents of the gastrointestinal tract affect the rate of absorption, but not the degree of absorption, so it can be administered in mixed feeding. After taking the same dose orally, the serum concentration of amoxicillin is 1.5 to 3 times higher than that of ampicillin.
Drug Interactions
(1) Combination of this product with aminoglycosides can increase the concentration of the latter in bacteria, showing a synergistic effect. (2) Fast-acting bacteriostatic agents such as macrolides, tetracyclines and amide alcohols interfere with the bactericidal effect of this product, and should not be used together.
Action and use
β-lactam antibiotics. For the treatment of amoxicillin-susceptible gram-positive and gram-negative infections in chickens.
Dosage and Usage
Based on this product. Oral administration: one dose, per 1kg body weight, chicken 0.2-0.3g, twice a day, for 5 days; mixed drink: per 1L of water, chicken 0.6g, for 3-5 days.
Adverse reactions
It has a strong interference effect on the normal flora of the gastrointestinal tract.
Precautions
(1) It is forbidden for laying hens during the laying period.
(2) Gram-positive bacterial infection resistant to penicillin should not be used.
(3) Current allocation and use.
Withdrawal perio
7 days for chickens.
Storage
shading, sealed preservation
Hebei Veyong pharmaceutical Co., Ltd, was established in 2002, located in Shijiazhuang City, Hebei Province, China, next to the Capital Beijing. She is a large GMP-certified veterinary drug enterprise, with R&D, production and sales of veterinary APIs, preparations, premixed feeds and feed additives. As Provincial Technical Center, Veyong has established an innovated R&D system for new veterinary drug, and is the nationally known technological innovation based veterinary enterprise, there are 65 technical professionals. Veyong has two production bases: Shijiazhuang and Ordos, of which the Shijiazhuang base covers an area of 78,706 m2, with 13 API products including Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, and 11 preparation production lines including injection, oral solution, powder, premix, bolus, pesticides and disinfectant, ects. Veyong provides APIs, more than 100 own- label preparations, and OEM & ODM service.
Veyong attaches great importance to the management of EHS(Environment, Health& Safety) system, and obtained the ISO14001 and OHSAS18001 certificates. Veyong has been listed in the strategic emerging industrial enterprises in Hebei Province and can ensure the continuous supply of products.
Veyong established the complete quality management system, obtained the ISO9001 certificate, China GMP certificate, Australia APVMA GMP certificate, Ethiopia GMP certificate, Ivermectin CEP certificate, and passed US FDA inspection. Veyong has professional team of registeration, sales and technical service, our company has gained reliance and support from numerous customers by excellent product quality, high-quality pre-sales and after-sales service, serious and scientific management. Veyong has made long term cooperation with many internationally known animal pharmaceutical enterprises with products exported to the Europe, South America, Middle East, Africa, Asia, etc. more than 60 countries and regions.
