Penstrep 20/20 Injection
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Composition
Per ml Suspension
Procaine Penicillin-20g
Dihydrostreptomycin sulphate-20g
Function
The antibacterial spectrum and mechanism of procaine penicillin are the same as penicillin. It mainly acts on moderate and mild infections caused by gram-positive cocci that are sensitive to penicillin. Penicillin has good antibacterial activity against Streptococcus hemolyticus, Streptococcus pneumoniae, and Staphylococcus that does not produce penicillinase. Neisseria gonorrhoeae, Neisseria meningitidis, Corynebacterium diphtheria, Bacillus anthracis, Actinomyces bovis, Streptobacter candida, Listeria, Leptospira and Treponema pallidum are sensitive to this product. This product also has antibacterial activity against Haemophilus influenzae and Bordetella pertussis. This product has a good antibacterial effect on anaerobic bacteria such as Clostridium, Peptostreptococcus and Bacteroides melanogaster, but has a poor antibacterial effect on Bacteroides fragilis. Penicillin plays a bactericidal effect by inhibiting the synthesis of bacterial cell walls.
Dihydrostreptomycin is suitable for the treatment of infections caused by a variety of Gram-negative bacteria, such antibiotics have the advantages of strong bactericidal activity, low toxicity, wide indications and good clinical efficacy.
Indications
Infections, like respiratory, uterine and alimentary tract infections, Metritis, Mastitis, Osteomyelitis, peritonitis, Septicaemia, Cysisisjoint-ill and secondary bacterial infections, in horses, cattle, pigs, foals, calves, sheep and goats
Dosage and Administration
Intramuscular administration:1 ml per 25kg, Live weight per day, for 3 to 4 days; In severe cases, this dosage may be doubled
Note: shake well before use .
Drug interactions
1. It has a synergistic effect when combined with penicillins or cephalosporins.
2. The antibacterial effect of this class of drugs is enhanced in alkaline environment, and the combination of alkaline drugs (such as sodium bicarbonate, aminophylline, etc.) can enhance the antibacterial effect, but the toxicity is also correspondingly enhanced. When the pH value exceeds 8.4, the antibacterial effect is weakened.
3.Cations such as Ca, Mg2+, Nat, NH and K can inhibit the antibacterial activity of this class of drugs.
4.Combination with cephalosporin, dextran, potent diuretics (such as furosemide, etc.), erythromycin, etc., can enhance the ototoxicity of this class of drugs.
5.Skeletal muscle relaxants (such as succinylcholine chloride, etc.) or drugs with such effects can strengthen the neuromuscular resistance of this class of drugs.
Withdrawal Period
Meat: 10 days/ days ;Milk:3 days
Storage
Store in a cool place, below 25℃, away from light.
Hebei Veyong pharmaceutical Co., Ltd, was established in 2002, located in Shijiazhuang City, Hebei Province, China, next to the Capital Beijing. She is a large GMP-certified veterinary drug enterprise, with R&D, production and sales of veterinary APIs, preparations, premixed feeds and feed additives. As Provincial Technical Center, Veyong has established an innovated R&D system for new veterinary drug, and is the nationally known technological innovation based veterinary enterprise, there are 65 technical professionals. Veyong has two production bases: Shijiazhuang and Ordos, of which the Shijiazhuang base covers an area of 78,706 m2, with 13 API products including Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, and 11 preparation production lines including injection, oral solution, powder, premix, bolus, pesticides and disinfectant, ects. Veyong provides APIs, more than 100 own- label preparations, and OEM & ODM service.
Veyong attaches great importance to the management of EHS(Environment, Health& Safety) system, and obtained the ISO14001 and OHSAS18001 certificates. Veyong has been listed in the strategic emerging industrial enterprises in Hebei Province and can ensure the continuous supply of products.
Veyong established the complete quality management system, obtained the ISO9001 certificate, China GMP certificate, Australia APVMA GMP certificate, Ethiopia GMP certificate, Ivermectin CEP certificate, and passed US FDA inspection. Veyong has professional team of registeration, sales and technical service, our company has gained reliance and support from numerous customers by excellent product quality, high-quality pre-sales and after-sales service, serious and scientific management. Veyong has made long term cooperation with many internationally known animal pharmaceutical enterprises with products exported to the Europe, South America, Middle East, Africa, Asia, etc. more than 60 countries and regions.
