Closantel Sodium
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Closantel Sodium
Closantel sodium is a broad-spectrum anthelmintic, which has a good effect on a variety of trematodes, nematodes and arthropod larvae; its anti-fluke repellent activity is mainly against Fasciola hepatica, anti-nematodes and The larval repellent activity against arthropods is mainly aimed at all kinds of worms that suck blood or plasma.
This product is widely used in various infections of the above-mentioned parasitic diseases in cattle and sheep. It can be administered orally or parenterally (subcutaneously and intramuscularly), and it has both therapeutic and preventive effects. There are injections, pills and soaking agents on the market. Generally, it is compatible with mebendazole and other benzimidazole products to make a composite soaking agent for sheep; it is compatible with levamisole to make a composite pill for cattle.
Mode of action and characteristics
Closalamide sodium is also known as chlorsalamide sodium salt and chlorsalamide sodium salt. It belongs to the same salicylanilide compound as iodosalamide and is a new type of broad-spectrum anti-parasitic currently used in the breeding industry. Insect medicine, the appearance is slightly yellow powder, odorless or slightly smelly, easily soluble in ethanol or acetone, soluble in methanol, and insoluble in water or chloroform. The pharmacological action is to inhibit the mitochondrial phosphorylation process of the worms, thereby preventing the synthesis of adenosine triphosphate (ATP) in the worms, leading to the rapid weakening of the energy metabolism of the worms and finally death. Closantel sodium can completely kill scabies mites, blood lice, roundworms, strongyloides, kidney nematodes, whipworms, Burrow nematodes, supine mouth nematodes, radiation esophagus Flukes, capillary nematodes, skin fly maggots, sheep nose fly maggots, ticks, scabies, itch mites, nematodes, Fasciola hepatica, horse stomach flies, lipoma canis and other poultry internal and external parasites. It has a good effect on the larvae of a variety of trematodes, nematodes and arthropods; its anti-fluke repellent activity is mainly for Fasciola hepatica, and its larval repellent activity against nematodes and arthropods is mainly for a variety of suckers. The worm body of blood or plasma. Clinical efficacy tests have shown that when administered at a dose of 10 mg/kg body weight, it has complete repelling effect on sheep Fasciola hepatica, anterior and posterior disc trematode, lungworm and most of the digestive tract nematodes in and out of the body. It is the best deworming effect in sheep. The best dosage.
Preparations
5% ,10% Closantel sodium injection;
1% Ivermectin +12.5% Closantel sodium injection;
5%, 10% Closantel sodium suspension.
Hebei Veyong pharmaceutical Co., Ltd, was established in 2002, located in Shijiazhuang City, Hebei Province, China, next to the Capital Beijing. She is a large GMP-certified veterinary drug enterprise, with R&D, production and sales of veterinary APIs, preparations, premixed feeds and feed additives. As Provincial Technical Center, Veyong has established an innovated R&D system for new veterinary drug, and is the nationally known technological innovation based veterinary enterprise, there are 65 technical professionals. Veyong has two production bases: Shijiazhuang and Ordos, of which the Shijiazhuang base covers an area of 78,706 m2, with 13 API products including Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, and 11 preparation production lines including injection, oral solution, powder, premix, bolus, pesticides and disinfectant, ects. Veyong provides APIs, more than 100 own- label preparations, and OEM & ODM service.
Veyong attaches great importance to the management of EHS(Environment, Health& Safety) system, and obtained the ISO14001 and OHSAS18001 certificates. Veyong has been listed in the strategic emerging industrial enterprises in Hebei Province and can ensure the continuous supply of products.
Veyong established the complete quality management system, obtained the ISO9001 certificate, China GMP certificate, Australia APVMA GMP certificate, Ethiopia GMP certificate, Ivermectin CEP certificate, and passed US FDA inspection. Veyong has professional team of registeration, sales and technical service, our company has gained reliance and support from numerous customers by excellent product quality, high-quality pre-sales and after-sales service, serious and scientific management. Veyong has made long term cooperation with many internationally known animal pharmaceutical enterprises with products exported to the Europe, South America, Middle East, Africa, Asia, etc. more than 60 countries and regions.
