Doxycycline+Tylosin Soluble Powder
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Pharmacological action
Pharmacodynamics Tylosin is an animal-specific macrolide antibiotic with strong effect on mycoplasma. The antibacterial spectrum is similar to that of erythromycin, and the sensitive Gram-positive bacteria are Staphylococcus aureus (including penicillin-resistant Staphylococcus aureus), pneumococcus, streptococcus, Bacillus anthracis, Erysipelothrix rhusiopathiae, Listeria monocytogenes, Portunus putrefaciens, and Portunus emphysematosus. Sensitive gram-negative bacteria include Haemophilus, meningococcus and Pasteurella. Sensitive bacteria can develop resistance to this product, and Staphylococcus aureus has partial cross-resistance to this product and erythromycin.
Pharmacokinetics
Tylosin can be absorbed from the gastrointestinal tract after oral administration, and peak concentrations are reached 1 hour after oral administration in pigs, while tylosin phosphate is less absorbed. Tylosin is widely distributed in the body after absorption, and the organ concentration after injection is 2 to 3 times higher than that after oral administration, but it is not easy to penetrate into the cerebrospinal fluid.
Drug interactions
(1) It should not be used at the same time because it has the same target as other macrolides, lincosamines and amide alcohols.
(2), the combination with β-lactams showed antagonism.
Hebei Veyong pharmaceutical Co., Ltd, was established in 2002, located in Shijiazhuang City, Hebei Province, China, next to the Capital Beijing. She is a large GMP-certified veterinary drug enterprise, with R&D, production and sales of veterinary APIs, preparations, premixed feeds and feed additives. As Provincial Technical Center, Veyong has established an innovated R&D system for new veterinary drug, and is the nationally known technological innovation based veterinary enterprise, there are 65 technical professionals. Veyong has two production bases: Shijiazhuang and Ordos, of which the Shijiazhuang base covers an area of 78,706 m2, with 13 API products including Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, and 11 preparation production lines including injection, oral solution, powder, premix, bolus, pesticides and disinfectant, ects. Veyong provides APIs, more than 100 own- label preparations, and OEM & ODM service.
Veyong attaches great importance to the management of EHS(Environment, Health& Safety) system, and obtained the ISO14001 and OHSAS18001 certificates. Veyong has been listed in the strategic emerging industrial enterprises in Hebei Province and can ensure the continuous supply of products.
Veyong established the complete quality management system, obtained the ISO9001 certificate, China GMP certificate, Australia APVMA GMP certificate, Ethiopia GMP certificate, Ivermectin CEP certificate, and passed US FDA inspection. Veyong has professional team of registeration, sales and technical service, our company has gained reliance and support from numerous customers by excellent product quality, high-quality pre-sales and after-sales service, serious and scientific management. Veyong has made long term cooperation with many internationally known animal pharmaceutical enterprises with products exported to the Europe, South America, Middle East, Africa, Asia, etc. more than 60 countries and regions.
