5% Oxytetracycline Injection
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Composition
Each 100ml contains 5g oxytetracycline hydrochloride
Appearance
5% Oxytetracycline injection is amber clear liquid with special odor.
Usage and Dosage
Intramuscular injection: One dose, 0.2~0.4ml for livestock per 1kg body weight.
Pharmacological action
Oxytetracycline is a broad-spectrum antibiotic of the tetracycline class. It has a strong effect on gram-positive bacteria such as Staphylococcus, Streptococcus hemolyticus, Bacillus anthracis, Clostridium tetani and Clostridium, but it is not as good as β-lactams. It is more sensitive to Gram-negative bacteria such as Escherichia coli, Salmonella, Brucella and Pasteurella, but not as good as aminoglycosides and amide alcohol antibiotics. This product also has inhibitory effects on rickettsia, chlamydia, mycoplasma, spirochetes, actinomycetes and certain protozoa.
Adverse reactions
(1) Local irritation. The hydrochloride aqueous solution of this class of drugs has strong irritation, and intramuscular injection can cause pain, inflammation and necrosis at the injection site.
(2) Disorders of intestinal flora. Tetracyclines have a broad-spectrum inhibitory effect on equine intestinal bacteria, and then secondary infections caused by drug-resistant Salmonella or unknown pathogens (including Clostridium, etc.) lead to severe or even fatal diarrhea. This situation often occurs after high-dose intravenous administration, but may also occur after low-dose intramuscular injection.
(3) Affect the development of teeth and bones. Tetracyclines are combined with calcium after entering the body, and are deposited in teeth and bones along with calcium. This class of drugs is also easy to pass through the placenta and enter the milk. Therefore, pregnant animals, lactating animals and small animals are forbidden, and milk for lactating cows is prohibited from being marketed during the medication period.
(4) Liver and kidney damage. This class of drugs has toxic effects on liver and kidney cells. Tetracycline antibiotics can cause dose dependence in a variety of animals
Sexual kidney function changes.
(5) Anti-metabolism effect. Tetracycline drugs can cause azotemia, and it can be exacerbated by the presence of steroid drugs. This class of drugs
It can also cause metabolic acidosis and electrolyte imbalance.
Precautions
(1) 5% Oxytetracycline injection should be kept away from light and airtight, and stored in a cool, dark and dry place. Avoid B light exposure. Do not use metal containers for medicines.
(2) Horses may also develop gastroenteritis after injection, so it should be used with caution.
(3) Avoid use when the liver and kidney function of the animal is severely damaged.
Withdrawal period
28 days for cattle, sheep and pigs; 7 days for abandonment period
Storage
Protect from sunlight,Store in the place below 30℃,
Hebei Veyong pharmaceutical Co., Ltd, was established in 2002, located in Shijiazhuang City, Hebei Province, China, next to the Capital Beijing. She is a large GMP-certified veterinary drug enterprise, with R&D, production and sales of veterinary APIs, preparations, premixed feeds and feed additives. As Provincial Technical Center, Veyong has established an innovated R&D system for new veterinary drug, and is the nationally known technological innovation based veterinary enterprise, there are 65 technical professionals. Veyong has two production bases: Shijiazhuang and Ordos, of which the Shijiazhuang base covers an area of 78,706 m2, with 13 API products including Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, and 11 preparation production lines including injection, oral solution, powder, premix, bolus, pesticides and disinfectant, ects. Veyong provides APIs, more than 100 own- label preparations, and OEM & ODM service.
Veyong attaches great importance to the management of EHS(Environment, Health& Safety) system, and obtained the ISO14001 and OHSAS18001 certificates. Veyong has been listed in the strategic emerging industrial enterprises in Hebei Province and can ensure the continuous supply of products.
Veyong established the complete quality management system, obtained the ISO9001 certificate, China GMP certificate, Australia APVMA GMP certificate, Ethiopia GMP certificate, Ivermectin CEP certificate, and passed US FDA inspection. Veyong has professional team of registeration, sales and technical service, our company has gained reliance and support from numerous customers by excellent product quality, high-quality pre-sales and after-sales service, serious and scientific management. Veyong has made long term cooperation with many internationally known animal pharmaceutical enterprises with products exported to the Europe, South America, Middle East, Africa, Asia, etc. more than 60 countries and regions.
