Tylvalosin Tartrate
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Pharmacology and Toxicology
Tylvalosin has antibacterial activity against a variety of Gram-positive bacteria, such as Staphylococcus, Micrococcus, Microbacteria, Bacillus, Corynebacterium, Balloon bacteria, Campylobacter, Enterococcus, Streptococcus, Arthrobacter, etc.; Mycoplasma also has good antibacterial activity and works better at high concentrations; but it has no effect on most Gram-negative bacteria.
Pharmacological action
1.The most effective animal antibiotics in Mycoplasma suis and ileitis maintain the normal function of the immune system of the respiratory mucosa to prevent pathogen escape. Treatment with Mycoplasma suis rapidly enters intestinal epithelial cells and acts on the ribosomes of intracellular Lawsonia to kill bacteria.
2.Improve overall immunity by promoting macrophage metabolism and increasing the number of macrophages and lysosomal proteins in macrophages.
3.Prevent PRRS replication.
Indication
Pigs: Treatment and methaphylaxis of swine enzootic pneumonia; Treatment of porcine proliferative enteropathy (ileitis); Treatment and methaphylaxis of swine dysentery.
Chickens:Treatment and methaphylaxis of respiratory disease associated with Mycoplasma gallisepticum in chickens.,
Turkeys: Treatment of respiratory disease associated with tylvalosin sensitive strains of Ornithobacterium rhinotracheale in turkeys.
Clinical application and adverse reactions
Tylvalosin preparations (such as premixes, soluble powders and granules) can be used clinically to prevent and treat swine asthma caused by Mycoplasma suis, swine dysentery caused by B. hyodysenteriae, and Lawsonia intracellularis Porcine proliferative enteritis and Mycoplasma gallisepticum infection caused by Mycoplasma gallisepticum. Multiple field trials have confirmed that Tyvanectin has a significant effect on the treatment of swine asthma, swine dysentery and porcine proliferative enteritis, with high safety and no adverse reactions. Researchers administer the test pigs at 5 times, 10 times or even 20 times the recommended dose. The study found that tyvans had no effect on the pig’s body weight, feed intake, hematology, blood biochemistry, histopathology, etc., which was sufficient. It shows that tyvans has no adverse reactions when used on pigs, and it has high safety.
Advantage
No withdrawal period (0 days);
Wide safety margin
Preparations
Tylvalosin premix; Tylvalosin solution; Tylvalosin tartrate premix 20%, 50%
Content
≥ 98%
Packing
25kg/cardboard drum
Hebei Veyong pharmaceutical Co., Ltd, was established in 2002, located in Shijiazhuang City, Hebei Province, China, next to the Capital Beijing. She is a large GMP-certified veterinary drug enterprise, with R&D, production and sales of veterinary APIs, preparations, premixed feeds and feed additives. As Provincial Technical Center, Veyong has established an innovated R&D system for new veterinary drug, and is the nationally known technological innovation based veterinary enterprise, there are 65 technical professionals. Veyong has two production bases: Shijiazhuang and Ordos, of which the Shijiazhuang base covers an area of 78,706 m2, with 13 API products including Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, and 11 preparation production lines including injection, oral solution, powder, premix, bolus, pesticides and disinfectant, ects. Veyong provides APIs, more than 100 own- label preparations, and OEM & ODM service.
Veyong attaches great importance to the management of EHS(Environment, Health& Safety) system, and obtained the ISO14001 and OHSAS18001 certificates. Veyong has been listed in the strategic emerging industrial enterprises in Hebei Province and can ensure the continuous supply of products.
Veyong established the complete quality management system, obtained the ISO9001 certificate, China GMP certificate, Australia APVMA GMP certificate, Ethiopia GMP certificate, Ivermectin CEP certificate, and passed US FDA inspection. Veyong has professional team of registeration, sales and technical service, our company has gained reliance and support from numerous customers by excellent product quality, high-quality pre-sales and after-sales service, serious and scientific management. Veyong has made long term cooperation with many internationally known animal pharmaceutical enterprises with products exported to the Europe, South America, Middle East, Africa, Asia, etc. more than 60 countries and regions.
